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NAD+ Therapy: Scientific Evidence and Benefits

LongevityClinics Team6/30/2026
NAD+ Therapy: Scientific Evidence and Benefits

NAD+ Therapy: Scientific Evidence and Benefits


NAD+ (Nicotinamide Adenine Dinucleotide) is essential for cellular health.


What is NAD+?


  • Coenzyme found in every cell
  • Essential for energy production
  • Critical for DNA repair
  • Declines with age (50% by age 60)

  • Scientific Evidence


    #### Anti-Aging

  • Activates sirtuins (longevity genes)
  • Improves mitochondrial function
  • Enhances DNA repair

  • #### Metabolic Health

  • Improves insulin sensitivity
  • Supports healthy weight
  • Enhances cellular metabolism

  • #### Brain Health

  • Neuroprotective effects
  • May help with neurodegenerative diseases
  • Improves cognitive function

  • Therapy Options


    #### IV NAD+

  • Direct delivery to bloodstream
  • Rapid elevation of NAD+ levels
  • Effects felt immediately
  • Cost: $250-1000 per session

  • #### NMN Supplements

  • Oral precursor to NAD+
  • Gradual elevation over weeks
  • Convenient daily dosing
  • Cost: $30-60/month

  • Dosage Recommendations


  • **IV NAD+**: 500-1000mg per session
  • **NMN**: 250-1000mg daily
  • **NR**: 300-1000mg daily

  • Key Takeaways


    1. NAD+ declines significantly with age

    2. Both IV and oral options are effective

    3. Scientific evidence is strong

    4. Consult with qualified practitioners

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