Longevity Supplements: Scientific Review

Which supplements actually work for extending healthy lifespan?

#### NMN (Nicotinamide Mononucleotide)

**Dose**: 250-1000mg daily

**Evidence**: Raises NAD+, improves metabolic health

**Cost**: $30-60/month

#### Resveratrol

**Dose**: 150-500mg daily

**Evidence**: Activates sirtuins, anti-inflammatory

**Cost**: $15-30/month

#### Metformin

**Dose**: 500-1500mg daily (prescription)

**Evidence**: Reduces aging markers

**Cost**: $10-30/month

#### Rapamycin

**Dose**: 3-6mg weekly (prescription)

**Evidence**: Extends lifespan in animals

**Cost**: $50-100/month

**Vitamin D3**: 2000-5000 IU daily

**Omega-3**: 2-3g daily

**Magnesium**: 200-400mg daily

**CoQ10**: 100-200mg daily

1. Consult doctor before starting

2. Quality matters (third-party tested)

3. Supplements complement lifestyle

4. Individual response varies

1. NMN has strongest evidence among supplements

2. Prescription options (metformin, rapamycin) show promise

3. Basic supplements are foundational

4. Lifestyle factors remain most important

Related articles